ACETOTHIOKINASE Meaning and
Definition
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Acetothiokinase is an enzyme that plays a crucial role in the metabolic pathway of sulfur assimilation in living organisms. Specifically, it is responsible for the phosphorylation of acetohydroxy acid (AHAS) to form acetolactate. This reaction occurs during the biosynthesis of the amino acids methionine and isoleucine.
Acetothiokinase is an essential enzyme found in bacteria, plants, and certain microorganisms. Its presence is particularly significant in organisms that rely on sulfur as a nutrient source. In these organisms, acetothiokinase helps regulate sulfur metabolism by facilitating the conversion of AHAS to acetolactate, which can then be further transformed into methionine or isoleucine through subsequent enzymatic reactions.
The reaction catalyzed by acetothiokinase involves the transfer of a phosphate group from adenosine triphosphate (ATP) to the AHAS molecule. This phosphorylation reaction is energetically favorable and requires the presence of magnesium ions as cofactors.
Overall, acetothiokinase plays a vital role in sulfur metabolism and amino acid biosynthesis, contributing to the overall growth and development of various organisms. Its activity is tightly regulated to ensure the appropriate balance of sulfur assimilation and amino acid production, allowing organisms to meet their metabolic needs efficiently.
Common Misspellings for ACETOTHIOKINASE
- zcetothiokinase
- scetothiokinase
- wcetothiokinase
- qcetothiokinase
- axetothiokinase
- avetothiokinase
- afetothiokinase
- adetothiokinase
- acwtothiokinase
- acstothiokinase
- acdtothiokinase
- acrtothiokinase
- ac4tothiokinase
- ac3tothiokinase
- acerothiokinase
- acefothiokinase
- acegothiokinase
- aceyothiokinase
- ace6othiokinase
- ace5othiokinase
Etymology of ACETOTHIOKINASE
The word "acetothiokinase" is a scientific term consisting of three components: "aceto-", "thio-", and "kinase".
1. "Aceto-" is derived from the Latin word "acetum", meaning "vinegar". In scientific terminology, "aceto-" typically refers to compounds containing the acetyl group (CH3CO-).
2. "Thio-" is derived from the Greek word "thiōn", meaning "sulfur". In scientific terminology, "thio-" generally indicates the presence of a sulfur atom or sulfur-containing functional groups.
3. "Kinase" is derived from the Greek word "kinēsis", meaning "movement" or "motion". In biology, a kinase is an enzyme that catalyzes the transfer of phosphate groups from ATP (adenosine triphosphate) to a substrate molecule, thus transferring energy.
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