RNA SPLICE SITE Meaning and
Definition
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RNA splice site refers to specific regions along an RNA molecule where the process of RNA splicing takes place. RNA splicing is a crucial step in gene expression, especially in eukaryotic organisms, where it involves removing the non-coding regions called introns from a pre-messenger RNA (pre-mRNA) molecule and joining the coding regions known as exons together to form the final mRNA molecule.
The RNA splice site typically consists of two key components: the 5' (pronounced five prime) splice site and the 3' (pronounced three prime) splice site. The 5' splice site, also called the donor site, marks the beginning of an intron and is usually characterized by a specific sequence of nucleotides, such as GU (guanine, uracil). The 3' splice site, also known as the acceptor site, defines the end of an intron and typically contains another nucleotide sequence, such as AG (adenine, guanine). These sequences serve as recognition sites for RNA splicing machinery, including small nuclear ribonucleoproteins (snRNPs) and other protein factors that facilitate the splicing process.
Recognition of the RNA splice sites by these splicing factors triggers the splicing machinery to assemble at the splice sites and form a large complex known as the spliceosome. The spliceosome then catalyzes the precise removal of the intron and joins the adjacent exons together by forming covalent bonds between the nucleotides, resulting in the production of a mature mRNA molecule. RNA splice sites play a critical role in determining the correct splicing patterns and ensuring the accurate production of functional proteins, contributing greatly to the complexity and diversity of the proteome.
Common Misspellings for RNA SPLICE SITE
- ena splice site
- dna splice site
- fna splice site
- tna splice site
- 5na splice site
- 4na splice site
- rba splice site
- rma splice site
- rja splice site
- rha splice site
- rnz splice site
- rns splice site
- rnw splice site
- rnq splice site
- rna aplice site
- rna zplice site
- rna xplice site
- rna dplice site
- rna eplice site
- rna wplice site
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